Exclusion Interface is extremely poorly constructed and is a huge waste of time. They refuse to listen to feedback about doing it efficiently with check boxes the way Avast and most other programs have implemented. There is no excuse for wasting customers time.
When I exclude folders for extremely useful programs that I use such as Auslogic Defrag and JetClean, they have recently decided to nevertheless (even though the exclusion is supposed to let them know to leave the program alone) uninstall, delete, and erase these programs. In the past MalwareBytes left these programs alone, but not anymore. I think that these free programs have some sort of harmless activity which is picked up as a PUP. You would think that if I mark the locations of these programs in the Exclusion Setting, then I would get around this problem, but in fact that does not help.
The only workaround is a complicated bunch of steps which finally allows me to have these programs keep running.
Finally, Malwarebytes released a version, sometime last year, that kept eating up memory, slowed down, and often crashed everyone's computer. Although an update eventually fixed the problem, there was no acknowledgement, nor an official apology to all users. No other security program has done anything so terrible in all the years that I have worked with and repaired computers. Obviously, Malwarebytes never ran an effective Beta test, because they should have caught this screwup before releasing such an update.
Prior to version 3, the program was excellent, problems started with version 3, various components refused to stay enabled and behaved in a bizarre manner. Eventually later 3.xxx appear to no longer show this problem, but on occasion on new installs, on new computers it still happens