RStudio has a well-designed interface that is user friendly & easy to get on with. It is coed-based, so it takes some time to learn this language - which is something a little bit intimidating to those who haven't worked as a coder before. However, it is not hard to learn, and once proficient, you can do so many things in R that takes forever in Excel or SPSS.
Extra point: RStudio is incredibly powerful, that it conjures up data within seconds.
It might be mu delusion, but when dataset is super large, RStudio seems to be operating tiny bit slower than R.
If you want to be proficient in R - start with using RStudio.
I work in a neuroscience lab, where we intensively use R to analyze neuro-signal data. By using RStudio, we were able to train all our research assistants so that they can use R to analyze data, and this makes everything so much easier. In the past, we have to use Excel or SPSS to analyze data, and putting data into Excel or SPSS has never stopped being a huge pain for everyone. Now with RStudio, just writing down some codes and it automatically drags the data we want. Also, in the past, after the data analysis, we need to pull out the data and create graphs, put them in powerpoint slide. If data changes, we have to start all over again, which will take forever. Now with RStudio, we simply create graphs and slides within R, and if our database changes, all those graphs and slides change automatically. It works so well, that we cannot think of going back to excel & powerpoint - there' simply no point of doing that.