Wrike has a very clean, user-friendly interface. You don't have to hunting for your work or get hung up on technical glitches or errors - you see what you need to see, when you want to see it. I like the different pipeline stages you can use as a multi-person project progresses. I also really like the new calendar feature that they rolled out, after a long time requesting a calendar view.
Would like to see Wrike extensions on Firefox too, not just Chrome. Can sometimes be slow, but not enough to disrupt my work in any significant manner (unlike other systems)
Look at it closely compared to other systems like Asana and Trello before making a decision.
We have a lot of back-and-forth between teams, and Wrike makes that easier to deal with. As a result, there's less frustration on an individual level and higher productivity across the department. I also personally really like the calendar view - it makes it easy to see what coming weeks look like, and if I need to work hard to get ahead and not get swamped.